QUANTITATIVE ESTIMATION OF MEGLITINIDE IN PHARMACEUTICAL

Abstract

A literal and specific Visible spectrophotometric method was raised for the estimation for Repaglinide in solid pharmaceutical dosage form. The λ-max of Repaglinide was found to be 243nm to both crude and marketed sample and is analysed using Beer-Lamberts law. Beer’s law was obeyed at the concentrations ranging 2-10μg/ml. The developed methods were absolute, definite, explicit and consistent and found to be ap roto type for routine determination for Repaglinide. The method was validated statistically and by recovery studies. The LOD (limit of detection) and LOQ (limit of quantification) for visible spectra were found to be 0.82μg/ml and1.011μg/ml. The correlation coefficient value was found to be 1.